ISCS 2015

TUTORIAL-II: Genomics, Proteomics and Computation Drug Design

Resource Persons for Lectures and hand-on tutorial: Ankita Singh (Genomics), Rahul Kaushik (Proteomics) , Abhilash Jayaraj (Drug Design) from Supercomputing facility for Bio Informatics and Computational Biology, IIT Delhi, New Delhi

Objective of tutorial: The two day tutorial will focus on state of the art techniques on novel gene finding, protein structure prediction and structure based drug discovery

12th December 2015 (Day 1)

Time	Sessions	Topic
8:30 AM- 10:00 AM	Session I	Introduction to genes and genomes Data extraction from NCBI NCBI BLAST: homologue gene finding and result interpretations
10:00 AM - 10:30 AM		Tea Break
10:30 AM- 12:00 PM	Session II	ORF finding tools Novel gene finding strategies using different tools
12:00 PM- 1:00 PM		Lunch Break
1:00 PM- 2:30 PM	Session III	Introduction of Protein Structure prediction Protein Sequence Database: Data extraction from UniprotKb Protein Secondary Structure Prediction: Present Status and Softwares.
2:30 PM- 3:00 PM		Tea Break
3:00 PM- 4:30 PM	Session IV	Protein Tertiary Structure Prediction: Online Servers and Standalone Software Quality Assessment of Predicted Model Structures Protein Structure Visualization and a tour of RCSB PDB

13th December 2015 (Day 2)

Time	Sessions	Topic
8:30 AM- 10:00 AM	Session I	Introduction to structure based Drug Design Drugs: their properties and sources The process of drug development
10:00 AM - 10:30 AM		Tea Break
10:30 AM- 12:00 PM	Session II	Active site Prediction Virtual screening Docking and scoring
12:00 PM- 1:00 PM		Lunch Break
1:00 PM- 2:30 PM	Session III	Mini Project*
2:30 PM- 3:00 PM		Tea Break
3:00 PM- 4:30 PM	Session IV	Mini Project

*Mini Project will include novel gene finding, protein structure prediction for a query sequence and active site prediction and docking.

Lecture outline:

Instructor
Ankita
Ms. Ankita Singh